INHIBITION OF DYRK1B SUPPRESSES INFLAMMATION IN ALLERGIC CONTACT DERMATITIS MODEL AND TH1/TH17 IMMUNE RESPONSE

Inhibition of DYRK1B suppresses inflammation in allergic contact dermatitis model and Th1/Th17 immune response

Abstract Allergic contact dermatitis (ACD) is a type IV hypersensitivity mainly mediated by Th1/Th17 immune response.Topical corticosteroid is currently the first-line treatment for allergic contact dermatitis (ACD) and systemic administration of immunosuppressive drugs are used in patients with Key Chains severe disseminated cases.However, increas

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A Novel 24-Pulse Rectification System

A novel autotransformer configuration for 24-pulse rectification is proposed that not only maintains the desired power quality but also enables a reduction in autotransformer equivalent power capacity, therefore lowering cost, volume, and weight of the overall 24-pulse rectification system.The significances of the proposed autotransformer configura

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Urticating setae of tarantulas (Araneae: Theraphosidae): Morphology, revision of typology and terminology and implications for taxonomy.

Tarantula urticating setae are modified setae located on the abdomen or pedipalps, which represent an effective defensive mechanism against vertebrate or invertebrate predators and intruders.They are also useful taxonomic tools as morphological characters facilitating the classification of UBIQUINOL 200MG New World theraphosid spiders.In the presen

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